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:: Volume 10, Issue 37 (Winter 1401 2023) ::
NPWJM 2023, 10(37): 34-43 Back to browse issues page
Investigating on pathophysiology of Irritable Bowel Syndrome (IBS) and its associating genetic derangements: A review study
Fatemeh Roshani , Ahmad Fazilat , Mohammad Reza Tohidkia , Mehdi Haghi
Tabriz University of Medical Sciences
Abstract:   (1035 Views)
Introduction: Irritable Bowel Syndrome (IBS) is known as a prevalent, long-term condition of the digestive system, which affect a significant proportion of societies.Methods: In the current study, we have reviewed and investigated on the conducted researches covering IBS pathophysiology and the genes associated  with the manifestation of the syndrome.Findings: Throughout the published literature about IBS, various environmental factors as well as the influence of particular genes have been introduced as the underlying causes of raising IBS. This study is an effort to review, assess and collect data on multiple causes which leads to IBS manifestation.Conclusion: Although no certain and definite cause of IBS was found throughout searched and reviewed articles, factors such as stresses, childhood events, previous bowel infection, neurotransmitter changes in brain and genetic alterations have been described and explained through articles. Diagnosing IBS should be done precautiously and primary examinations on inspecting organic diseases in the digestive system should take place prior to diagnosis of the syndrome
Article number: 4
Keywords: Irritable Bowel Syndrome, digestive system, Pathogenicity, pathophysiology
Full-Text [PDF 649 kb]   (357 Downloads)    
Type of Study: Review | Subject: Special
Received: 2023/02/22 | Accepted: 2023/02/22 | Published: 2023/03/20
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roshani F, fazilat A, Tohidkia M R, Haghi M. Investigating on pathophysiology of Irritable Bowel Syndrome (IBS) and its associating genetic derangements: A review study. NPWJM 2023; 10 (37) : 4
URL: http://npwjm.ajaums.ac.ir/article-1-947-en.html

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Volume 10, Issue 37 (Winter 1401 2023) Back to browse issues page
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