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:: Volume 3, Issue 7 (7-2015) ::
NPWJM 2015, 3(7): 33-37 Back to browse issues page
Evaluation of Antibacterial effect of Zataria multiflora alcoholic extract on Extended-spectrum beta-lactamase (ESBL) producing strains of E.coli Isolated from urinary tract infections in the Imam Reza hospital
Abstract:   (1624 Views)

Introduction: Escherichia coli (E. coli), is the most common bacteria that cause urinary tract infections in women. Nowaday, many strains of E.coli have been resistant to beta-lactam antibiotics and bacterial Beta-lactamases, have an important role. The aim of this study was to investigate the role of thyme alcoholic extract on Extended-spectrum betalactamase (ESBL) producing strains of E.coli

Methods: After preparing the alcoholic extract of Zataria multiflora, concentrations 25, 50, 100, 200 and 400 μg /ml of this extract on ESBL-producing isolates of E.Coli was investigated, by agar disk diffusion method.

Results: The results showed that the inhibitory effect of  Zataria multiflora alcoholic extract on the growth of ESBL-producing strains of E. coli in concentrations 100 and 400 μg /ml, was significantly increased .(P<0.05)

Conclusion: Based on this study results, the alcoholic extract of Zataria multiflora has considerable inhibitory effects on ESBL-producing E. coli strains, in vitro.

Keywords: Zataria multiflora, Escherichia coli, ESBL, Urinary tract infection
Full-Text [PDF 286 kb]   (1949 Downloads)    
Type of Study: Research | Subject: Special
Received: 2016/06/21 | Accepted: 2016/06/21 | Published: 2016/06/21
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Evaluation of Antibacterial effect of Zataria multiflora alcoholic extract on Extended-spectrum beta-lactamase (ESBL) producing strains of E.coli Isolated from urinary tract infections in the Imam Reza hospital. NPWJM. 2015; 3 (7) :33-37
URL: http://npwjm.ajaums.ac.ir/article-1-301-en.html


Volume 3, Issue 7 (7-2015) Back to browse issues page
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