TY - JOUR T1 - Comparison of the effectiveness standard three-drug regimen in the treatment of Helicobacter pylori in a row with the regime in 1390 in the city of Jahrom TT - مقایسه اثربخشی رژیم درمانی متوالی با رژیم سه دارویی استاندارد در درمان هلیکوباکترپیلوری در سال 1390 در شهرستان جهرم JF - npwjm JO - npwjm VL - 2 IS - 5 UR - http://npwjm.ajaums.ac.ir/article-1-214-en.html Y1 - 2015 SP - 177 EP - 182 KW - Helicobacterpylori KW - sequential regimen KW - eradication N2 - Introduction: H.pylori is a gram negative and spiral organism that infected half of the world people. This organism is responsible for almost peptic ulcers and also MALT Lymphoma and Gastric Adenocarcinoma. Different therapies are used for H.pylori eradication such as triple and quadruple drugs regimes.Recently, a new therapeutic regime is discovered for H. pylori eradication, is named “Sequential” regime that amount and duration of antibiotics usage are less than previous regimes. In this study, eradication rate of sequential regime is investigated in 2011 in patientsreffered to JahromHonari clinic. Methods: This study is a interventional-clinical trial study.50 patients with H.pylori infection treated by sequential therapy that is include of amoxicillin +PPI for 5 days and followed with clarithromycin + thinidazole +PPI for second 5 days. After 10 days treatment and 2 month follow up UBT test was done .After that, data was got analysis by SPSS software. Results: 41 of 50 patients (82%) were responsed to sequential regimes .and 43 of 50 patients (86%) were responsed to anther regime. Conclusion: In this study, no significant differences between the two treatments were observed, but the amount of the drug was used in the sequential treatment was lower and therefore its complication will be lower. M3 ER -