TY - JOUR JF - npwjm JO - NPWJM VL - 3 IS - 7 PY - 2015 Y1 - 2015/7/01 TI - Evaluation of Antibacterial effect of Zataria multiflora alcoholic extract on Extended-spectrum beta-lactamase (ESBL) producing strains of E.coli Isolated from urinary tract infections in the Imam Reza hospital TT - ارزیابی اثر ضد باکتریائی عصاره الکلی گیاه آویشن شیرازی بر روی سویه های "مولد بتالاکتاماز وسیع الطیف" باکتری اشریشیا کلی جدا شده از عفونتهای ادراری در بیمارستان امام رضا(ع) N2 - Introduction: Escherichia coli (E. coli), is the most common bacteria that cause urinary tract infections in women. Nowaday, many strains of E.coli have been resistant to beta-lactam antibiotics and bacterial Beta-lactamases, have an important role. The aim of this study was to investigate the role of thyme alcoholic extract on Extended-spectrum betalactamase (ESBL) producing strains of E.coli Methods: After preparing the alcoholic extract of Zataria multiflora, concentrations 25, 50, 100, 200 and 400 μg /ml of this extract on ESBL-producing isolates of E.Coli was investigated, by agar disk diffusion method. Results: The results showed that the inhibitory effect of Zataria multiflora alcoholic extract on the growth of ESBL-producing strains of E. coli in concentrations 100 and 400 μg /ml, was significantly increased .(P<0.05) Conclusion: Based on this study results, the alcoholic extract of Zataria multiflora has considerable inhibitory effects on ESBL-producing E. coli strains, in vitro. SP - 33 EP - 37 AD - KW - Zataria multiflora KW - Escherichia coli KW - ESBL KW - Urinary tract infection UR - http://npwjm.ajaums.ac.ir/article-1-301-en.html ER -