Background: Stress is a negative emotional experience and assessment of unreasonable events that will lead to environmental disturbance. Nursing is a difficult and stressful job. The contradiction between trying to provide care for patients and poor management policy on productivity and job satisfaction can lead to emotional exhaustion, decreased motivation and interest in the work environment, apathy, and emotional burnout syndrome.

Aims: The aim of this experimental study was to determine the effectiveness of stress management training and emotional regulation on job satisfaction of nurses. For this purpose 90 nurses working in Bushehr Shohadaye Khalij-e Fars hospital, randomly selected and divided into two case and control groups. The case group was trained for stress management and emotional regulation for three weeks.

Results: The results indicate the effectiveness of the intervention on overall job satisfaction (t=4.75, p<0.000) and also work subscale (t=3.95,p<0.001), supervision (t=2.10,p<0.05), promotion opportunities (t=4.53,p<0.000) and relationships with colleagues (t=4.83, p<0.001). But has no effect on wages and benefits subscales (t=1.38, p: not significant).The results showed that there is no gender difference but the function is correlated inversely with age.

Conclusion: Implementation of these interventions, in addition to increasing the productivity of nurses, copes with the challenges of their jobs and could decrease the psychological problems.