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Examination of serum and salivary creatinine levels in inflammatory bowel disease
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Peyman Aslani   , Iraj Mirzaii-Dizgah , Elahe Alavi Afrakoti , Mohammad Arbaghaei |
| Aja University of Medical Sciences |
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Abstract: (368 Views) |
Introduction: Inflammatory bowel disease (IBD) is a systemic and chronic disease of the digestive system that affects millions of people every year. Considering the possibility of renal involvement as an extra-intestinal manifestation of the disease, we decided to compare creatinine levels in serum and saliva of the affected and healthy groups.
Method: In a cross-sectional study, 30 subjects with IBD and 30 healthy subjects were included. Non-stimulated serum and saliva were collected in the morning and creatinine was measured photometrically. Data were analyzed by t-test using SPSS version 22 software. P<0.05 was considered significant.
Finding: 30 patients with IBD with a mean age of 37.7 ± 2.3 years and 30 healthy individuals with a mean age of 32.5 ± 2.2 years participated in this study. The body mass index of the IBD group was 25.5 ± 0.68 and that of the healthy group was 26.2 ± 1.34, and there was no significant difference in these parameters (p>0.05). The results also showed that the mean serum and salivary creatinine levels were not significantly different in the two groups.
Conclusion: It seems that creatinine levels do not change in patients with IBD and healthy people, and there is no renal involvement and no decline in renal function in the early years of the disease. |
Article number: 5 |
| Keywords: inflammatory bowel disease, creatinine, saliva, serum |
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Full-Text [PDF 238 kb]
(107 Downloads)
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Type of Study: Research |
Subject:
Special
Received: 2024/05/5 | Accepted: 2024/11/27 | Published: 2025/01/3
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